Global gene expression analysis of the Myxococcus xanthus developmental time course
نویسندگان
چکیده
منابع مشابه
Chemosensory regulation of developmental gene expression in Myxococcus xanthus.
The delta-proteobacterium Myxococcus xanthus coordinates its motility during aggregation and fruiting body formation. While searching for chemotaxis genes in M. xanthus, we identified a third chemotaxis-like gene cluster, the che3 cluster, encoding homologs to two methyl-accepting chemotaxis proteins (MCPs), a CheW, a hybrid CheA, a CheB, a CheR, but no CheY. Mutations in mcp3A, mcp3B, and cheA...
متن کاملRegulation of expression of the pilA gene in Myxococcus xanthus.
Type IV pili are required for social gliding motility in Myxococcus xanthus. In this work, the expression of pilin (the pilA gene product) during vegetative growth and fruiting-body development was examined. A polyclonal antibody against the pilA gene product (prepilin) was prepared, along with a pilA-lacZ fusion, and was used to assay expression of pilA in M. xanthus in different mutant backgr...
متن کاملDevelopmental cell interactions of Myxococcus xanthus: analysis of mutants.
A set of developmental mutants have been examined that behave as if defective in cellular interactions necessary for the formation of myxospores during fruiting body development. Sporulation is rescued in these mutants if they are mixed with wild-type cells. Complementation experiments with whole cells divide the mutants into four groups (A, B, C, and D). Mutants of group A appear to be less re...
متن کاملA combination of unusual transcription factors binds cooperatively to control Myxococcus xanthus developmental gene expression.
Myxococcus xanthus is a bacterium that undergoes multicellular development requiring coordinate regulation of multiple signaling pathways. One pathway governs aggregation and sporulation of some cells in a starving population and requires C-signaling, whereas another pathway causes programmed cell death and requires the MazF toxin. In response to starvation, the levels of the bifunctional trans...
متن کاملcis Elements necessary for developmental expression of a Myxococcus xanthus gene that depends on C signaling.
Cell contact-mediated C signaling coordinates morphogenesis and gene expression during development of Myxococcus xanthus. One promoter that depends on C signaling for transcription lies upstream of Omega4403, the site of a Tn5 lac insertion in the genome. The Omega4403 promoter has a C-box sequence centered at -49 bp that matches the consensus 5'-CAYYCCY-3', which is found in several C-signal-d...
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ژورنال
عنوان ژورنال: Genomics
سال: 2021
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2020.11.030